Aromasin is a very strong and very potent steroidal aromatase inhibitor of the suicidal type, and information within the packaging in prescription Aromasin describes the ability for Aromasin to reduce Estrogen levels by 85%, as evidenced by studies on breast cancer patients. Suicidal aromatase inhibitors such as Aromasin (Exemestane) serve to permanently inhibit and disable the aromatase enzyme to which it is bound to. This renders the enzyme inactive forever. The body will eventually manufacture more aromatase enzymes, but the currently bound enzymes are bound indefinitely, eliminating any risk for Estrogen rebound. This is unseen with the other two major aromatase inhibitors (Arimidex and Letrozole), which are non-suicidal aromatase inhibitors that are only bound to the aromatase enzyme for limited time periods before the aromatase inhibitors unbind and become metabolized. If a non-suicidal aromatase inhibitor is halted too abruptly, the circulating inhibited aromatase enzymes that have not been metabolized out of the body will then become free again, and begin aromatizing androgens into Estrogens at an often rapid rate. This is not the case with Aromasin.
It makes natural sense to realize that the properties and effects of Aromasin would then become a benefit for the anabolic steroid using athlete for the purpose of Estrogen control. The use among anabolic steroid using athletes is for the control of almost all Estrogen-related side effects: the manifestation of gynecomastia, water retention and bloating, rising blood pressure (as a result of water retention increases from Estrogen). This is in contrast with SERMs such as Nolvadex, which only serve to block gynecomastia. As with many aromatase inhibitors, Aromasin has also demonstrated to increase levels of endogenous Testosterone production in men, which will be discussed further in this profile.
Although Aromasin is regarded by many anabolic steroid users and bodybuilders as being far more effective and far more useful (due to the suicidal inhibition) than Arimidex, Arimidex still today remains far more popular among the anabolic steroid using community. This is simply because Arimidex was developed and released before Aromasin, and therefore anabolic steroid using bodybuilders and athletes took notice of it sooner. Aromasin (Exemestane) to a degree was, in a way, overlooked and missed by many. Today this is beginning to change, where many individuals are now noticing the superiority and advantages of Aromasin over Arimidex (of which there are many, which will be described in detail throughout this profile). Some of these advantages that are not seen in any other aromatase inhibitors include: suicide inhibition, stimulating increases in IGF-1 (Insulin Like Growth Factor 1), displays little incompatibility with other compounds (something not seen with other aromatase inhibitors), as well as offering less of a negative impact on cholesterol values (again, something unseen with other aromatase inhibitors).
Aromasin is extremely effective at 25mg daily for the reduction of serum circulating Estrogen levels in the body, as demonstrated earlier with its ability to reduce Estrogen by 85%.